Dr. Kenzo Tenma is a renowned Japanese brain surgeon working at a leading hospital in Germany. One night, Dr. Tenma risks his reputation and career to save the life of a critically wounded young boy over that of the town mayor who had been planning to support the hospital financially. A string of mysterious murders begin to occur soon after the operation, and Dr. Tenma emerges as the primary suspect despite no incriminating evidence. A doctor is taught to believe that all life is equal; however, when another series of murders occur in the surgeon's vicinity, Dr. Tenma's beliefs are shaken as his actions that night are shown to have much broader consequences than he could have imagined. Leaving behind his life as a surgeon he embarks on a journey across the country to unravel the mystery of the boy he saved.
In a man-made underground society, descendants of a banished generation vie for control of the crumbling city of Lux. Ichise, an orphan turned prize fighter, loses a leg and an arm to satisfy an enraged fight promoter. On the brink of death he is taken in by a young woman doctor and used as a guinea pig for the next evolution of Texhnolyze. With his new limbs, Ichise is taken under the wing of Oonishi, a powerful leader of Organ, an organization with some hold on Lux. As Ichise is drawn deeper into a war for territorial control of the city, he learns of his possible future from the young girl prophet Ran, who guides him from the shadows in his darkest times. With the explosion of the warfare, Ichise must uncover the truth about Lux and fight for his survival as he realizes his destiny. (Source: ANN)
In the year 2015, the Angels, huge, tremendously powerful, alien war machines, appear in Tokyo for the second time. The only hope for Mankind's survival lies in the Evangelion, a humanoid fighting machine developed by NERV, a special United Nations agency. Capable of withstanding anything the Angels can dish out, the Evangelion's one drawback lies in the limited number of people able to pilot them. Only a handful of teenagers, all born fourteen years ago, nine months after the Angels first appeared, are able to interface with the Evangelion. One such teenager is Shinji Ikari, whose father heads the NERV team that developed and maintains the Evangelion. Thrust into a maelstrom of battle and events that he does not understand, Shinji is forced to plumb the depths of his own inner resources for the courage and strength to not only fight, but to survive, or risk losing everything. (Source: AniDB)
NERV is being attacked by SEELE and Rei becomes one with Lillith. Together with the Spear of Longinus and the completed EVA-series, Shinji will decide whether or not mankind will cease to exist. He has to decide now if he wants to stay alive or be dead, but his decision will affect all of humanity. (Source: ANN)
In the year 2029, the barriers of our world have been broken down by the net and by cybernetics, but this brings new vulnerability to humans in the form of brain-hacking. When a highly-wanted hacker known as the "Puppet Master" begins involving them in politics, Section 9, a group of cybernetically enhanced cops, are called in to investigate and stop the Puppet Master. The pursuit will call into question what makes a human and what is the Puppet Master in a world where the distinction between human and machine is increasingly blurry. (Source: Anime News Network)
It's the year 2019, thirty-one years have passed since the start of World War III. A top-secret child with amazing powers of the mind breaks free from custody and accidentally gets a motorcycle gang involved in the project. This incident triggers psychic powers within one of the gang members, Tetsuo, and he is taken by the army to be experimented on. His mind has been altered and is now on the path of war, seeking revenge on the society that once called him weak. (Source: FUNimation)
"Henrietta" was an innocent little girl when her entire family was massacred and she was left for dead. She was rescued by a privately-owned social welfare organization and given cybernetic components over her battered body. Brainwashed by the organization, she and four other girls now work as cold-blooded assassins, doing the dirty work for the Italian government.(Source: Anime News Network)
In the year 2012 Japan was invaded by the Mu. Human-like beings from another dimension with blue blood. In the year 2015 Tokyo is attacked by invaders, who are repelled by a humanoid weapon called a Dolem. During the chaos, Ayato Kamina meets Reika Mishima, a classmate. During that same day, he is attacked by government officials but a woman named Haruka comes to his rescue, informing him that she was sent to get him by the Organization TERRA, and that Tokyo had been sealed in a time rift where time flows one third as fast as the outside world. He flees from Haruka onto a train where he sees Reika once more. Arriving at the Room of Rah, he follows her to a tremendous egg where the Dolem RahXephon is hatched from, and upon her singing his mother appears atop the Dolem that had stopped the TERRA Invasion. In the battle Ayato's mother is injured, and Ayato flees Tokyo Jupiter with Haruka upon seeing his mother's blue blood.
The Diclonius, a mutated homosapien that is said to be selected by God and will eventually become the destruction of mankind, possess two horns on their heads and have a "sixth sense" which gives them telekinetic abilities. Due to this dangerous power, they have been captured and isolated in laboratories by the government. Lucy, a young and psychotic Diclonius, manages to break free of her confines and brutally murders most of the guards in the laboratory where she is being held, only to be shot in the head as she makes her escape. She survives, falling off a cliff into the ocean and manages to drift along to a beach where two teenagers, Kouta and Yuka, discover her. Having lost her memories, she was named after the only thing that she can now say, "Nyuu," and the two allow her to stay at Kouta's home. However, it appears that the psychotic side of Lucy is not dead just yet... (Source: ANN - Revised)
Somewhere in the vast sea of the Internet, there's a website that can only be accessed at the stroke of midnight. Known as the Jigoku Tsushin, rumor has it that if you post a grudge there, the Jigoku Shoujo will appear and drag whoever torments you into the inferno. Very little is known about the girl - all we know for sure is that she lives with her equally enigmatic grandmother, that three magical straw dolls accompany and serve her, and that whenever a posting on the Jigoku Tsushin moves her, she becomes the Jigoku Shoujo.